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1. How Can Hantaviruses Kill Humans but Leave Mice Unaffected: An Evaluation of the Immune Response of Deer Mice to Sin Nombre Virus

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Sin Nombre Virus (SNV) is a hantavirus that causes high mortality (>38%) in humans. Deer mice (Peromyscus maniculatus) are the primary host of SNV, and unlike humans, deer mice infected with SNV have few outward signs or symptoms of disease. The reasons for such asymptomatic infection in deer mice of have not been well studied; however, this information may be useful in uncovering therapies that could reduce human SNV mortality. Therefore, the objective...
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